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Freethink

A new drug could repair stroke damage to memory and movement

When a patient suffers an ischemic stroke — when a clot chokes off the blood supply of vital oxygen and nutrients to the brain — those brain cells begin to die within minutes. The resulting tissue damage can lead to long term complications, including paralysis, memory loss, depression, difficulty controlling emotions, and changes in behavior.
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MedicalXpress

New test may predict COVID immunity

Most people in the United States have some degree of immune protection against COVID-19, either from vaccination, infection, or a combination of the two. But, just how much protection does any individual person have?. MIT researchers have now developed an easy-to-use test that may be able to answer that question....
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MedicalXpress

New inhaled COVID-19 therapeutic blocks viral replication in the lungs

Scientists at the University of California, Berkeley, have created a new COVID-19 therapeutic that could one day make treating SARS-CoV-2 infections as easy as using a nasal spray for allergies. The therapeutic uses short snippets of synthetic DNA to gum up the genetic machinery that allows SARS-CoV-2 to replicate within...
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Daily Californian

Campus team develops nasal spray, blocks COVID-19 replication in lungs

A team of researchers at the Näär Lab at UC Berkeley have developed a new inhalable drug that blocks the viral replication of SARS-CoV-2 in lung cells. The drug is a type of antisense oligonucleotide, or ASO. These are small pieces of DNA or RNA that can bind to RNA strands and stop them from working in various ways. The drug has been tested on mice and hamsters so far, with human trials forthcoming.
BERKELEY, CA
MedicalXpress

Researchers find a way to help slow the next epidemic

Following two years of severe restrictions, everyone is eager to be done with the coronavirus pandemic. It's tempting to think that COVID-19 is history, but the coronavirus and other viruses will regularly resurface. What will we do the next time we have a major outbreak?. An NTNU research team has...
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ScienceBlog.com

New injectable gel offers promise for glioblastoma

Like the hardiest weed, glioblastoma almost always springs back — usually within months after a patient’s initial brain tumor is surgically removed. That is why survival rates for this cancer are just 25 percent at one year and plummet to 5 percent by the five-year mark. One of...
MADISON, WI
Futurity

COVID test identifies variants with 100% accuracy

A new COVID-19 test detects and identifies specific SARS-CoV-2 variants with 100% accuracy, researchers say. In a study, the RNA-encoded viral nucleic acid analytic reporter correctly determined the Alpha, Gamma, Delta, Epsilon, and Omicron genetic mutations in nasopharyngeal clinical samples. This ability could enable health care providers to make personalized...
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MedicalXpress

Scientists create long-acting injectable drug delivery system for tuberculosis

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments. To address that problem, scientists at the UNC School of Medicine, the UNC Institute for Global Health and Infectious Diseases, and the International Center for the Advancement of Translational Science developed a long-acting injectable formulation of the anti-TB drug rifabutin.
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technologynetworks.com

New Inhaled COVID-19 Therapy “Hacks" Viral Replication Machinery

Scientists at the University of California, Berkeley, have created a new COVID-19 therapeutic that could one day make treating SARS-CoV-2 infections as easy as using a nasal spray for allergies. The therapeutic uses short snippets of synthetic DNA to gum up the genetic machinery that allows SARS-CoV-2 to replicate within...
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Science Daily

Future medical applications in drug design

Morphogens are molecules that travel from biological cell to cell to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult during tissue repair. However, the way these morphogens are distributed to ensure patterning occurs is still not fully understood.
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